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RecruitingNCT07313527

PCR for Aspergillus Fumigatus in Blood and Bronchoalveolar Lavage Fluid for Monitoring Cases of Invasive Aspergillosis: What is Its Prognostic Value

Status
Recruiting
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
University Hospital, Strasbourg, France · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Aspergillus fumigatus PCR is currently used in conjunction with serum galactomannan to support the diagnosis of invasive aspergillosis or for monitoring at-risk patients not receiving antifungal prophylaxis. A positive result and a high titer are thought to be associated with the advanced stage of the disease and the fungal load. However, there is limited data on this subject, and no study has primarily focused on the variation of PCR levels during treatment and its potential correlation with treatment efficacy.

Conditions

Timeline

Start date
2025-03-17
Primary completion
2026-02-01
Completion
2026-02-01
First posted
2026-01-02
Last updated
2026-01-02

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT07313527. Inclusion in this directory is not an endorsement.

PCR for Aspergillus Fumigatus in Blood and Bronchoalveolar Lavage Fluid for Monitoring Cases of Invasive Aspergillosis: (NCT07313527) · Clinical Trials Directory