NCT07312825

Effectiveness of Combined Fascial Plane Blocks for Postoperative Pain in Gynecologic Oncology Surgery

Postoperative Analgesic Efficacy of Combined Fascial Plane Blocks After Gynecologic Oncologic Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 94 (actual)
• Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this prospective observational study is to compare the effectiveness of different postoperative analgesic techniques in patients undergoing major abdominal surgery for gynecologic oncology. The main question is whether the combination of TAP block with Quadratus Lumborum Block (QLB) or Rectus Sheath Block (RSB) provides superior pain relief compared to TAP block alone. All blocks were performed as part of routine clinical anesthesia practice according to the attending anesthesiologist's judgment. No randomization, allocation, or study-directed intervention was performed. Patients were classified into three groups based on the block type they received during standard care: Group 1: TAP Block Only Group 2: TAP + QLB Combination Group 3: TAP + RSB Combination Postoperative data, including pain scores (VAS), opioid consumption, sedation level, heart rate, blood pressure, nausea/vomiting, and length of hospital stay, were collected prospectively. The study aims to determine which block combination provides the best postoperative pain control and recovery profile in patients undergoing gynecologic oncology surgery.

Detailed description

This study is a prospective observational research designed to evaluate the postoperative analgesic effectiveness of different combinations of fascial plane blocks in patients undergoing gynecologic oncology surgery. All blocks (Transversus Abdominis Plane \[TAP\] block, Quadratus Lumborum Block \[QLB\], and Rectus Sheath Block \[RSB\]) were performed as part of routine clinical anesthesia practice according to the attending anesthesiologist's preference. No intervention, randomization, or protocol-directed procedure was applied for research purposes. After data collection, patients were classified into three groups based on the block type they had received in standard care: TAP block only TAP + QLB combination TAP + RSB combination The study prospectively compared postoperative pain scores (VAS), opioid consumption, time to mobilization, bowel function recovery, and length of hospital stay among these groups to determine the most effective analgesic strategy within routine practice. This observational design reflects real-world anesthesia management and does not involve any experimental or interventional component.

Conditions

• Gynecologic Cancers
• Postoperative Pain Management

Interventions

Type	Name	Description
OTHER	Group 1:The Transversus Abdominis Plane (TAP) block	Patients who received only Transversus Abdominis Plane (TAP) block as part of routine clinical anesthesia practice. No study-assigned intervention or randomization was performed. Data were collected prospectively from standard anesthesia records.
OTHER	Group 2: TAP Block + Quadratus Lumborum Block (QLB)	Patients who received TAP block combined with Quadratus Lumborum Block (QLB) during routine anesthesia management. This block combination was chosen by the attending anesthesiologist as part of standard care, not assigned by the study.
OTHER	Group 3: TAP Block + Rectus Sheath Block (RSB)	Patients who received TAP block combined with Rectus Sheath Block (RSB) as part of routine anesthesia practice. The block technique was performed according to clinical judgment, not as part of a study intervention.

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-01-01
• Completion: 2025-03-20
• First posted: 2025-12-31
• Last updated: 2025-12-31

Locations

1 site across 1 country: Turkey (Türkiye)