NCT07311642

The Effect of Intraoperative Binaural Beats on Remimazolam Dose Required for Maintenance of General Anesthesia

The Effect of Intraoperative Binaural Beats on Remimazolam Dose Required for Maintenance of General Anesthesia: a Randomized, Placebo-controlled Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 88 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

This prospective randomized controlled trial evaluates whether intraoperative binaural beats reduce the remimazolam dose required for general anesthesia in 88 adults undergoing breast surgery. Patients are assigned to binaural beats or silent earphones, and the primary outcome is total intraoperative remimazolam consumption.

Conditions

• Breast Reconstruction

Interventions

Type	Name	Description
DEVICE	biaural beat	Participants receive binaural beats via earphones from OR entry until end of surgery.
DEVICE	control	Participants wear identical earphones but receive no audio stimulation.

Timeline

• Start date: 2026-01-31
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2025-12-31
• Last updated: 2025-12-31