Trials / Completed
CompletedNCT07311447
Target-Controlled Infusion and Postoperative Neurocognitive Outcomes in Geriatric Patients
The Effect of Target-Controlled Infusion (TCI) on Neurocognitive Functions in Postoperative Sedoanalgesia Management in Geriatric Patients Undergoing Major Surgery
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- Namigar Turgut · Academic / Other
- Sex
- All
- Age
- 65 Years
- Healthy volunteers
- Not accepted
Summary
This prospective observational study aims to evaluate the effects of target-controlled infusion (TCI) on postoperative neurocognitive function in geriatric patients undergoing major non-cardiac surgery. Elderly patients are at increased risk of postoperative cognitive dysfunction due to physiological changes and anesthesia-related factors. In this study, sedation management with TCI will be compared to manual infusion. Neurocognitive function will be assessed at multiple time points using the Mini-Mental State Examination (MMSE), and sedation levels will be monitored with the Bispectral Index (BIS) and the Richmond Agitation-Sedation Scale (RASS). The study aims to provide insights into safer sedation practices and improved cognitive outcomes in elderly surgical patients.
Conditions
- Postoperative Cognitive Dysfunction (POCD)
- Neurocognitive Function
- Sedation and Analgesia
- Geriatric Patients
Timeline
- Start date
- 2025-05-05
- Primary completion
- 2025-10-31
- Completion
- 2025-10-31
- First posted
- 2025-12-31
- Last updated
- 2025-12-31
Locations
1 site across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT07311447. Inclusion in this directory is not an endorsement.