Trials / Not Yet Recruiting
Not Yet RecruitingNCT07308171
Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.
Detailed description
Nasal stimulation is generated by breathing, which enables olfaction and helps to rhythm brain activity. The loss of nasal stimulation in tracheotomized patients who are dependent on mechanical ventilation may negatively affect respiratory drive and contribute to dyspnea. Restoring nasal airflow therefore emerges as an attractive non-pharmacological approach to treat dyspnea in patients undergoing mechanical ventilation weaning. The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Baseline | patient ventilated through the tracheostomy with initial ventilator settings |
| PROCEDURE | Installation of high flow humidified air cannula | Installation of high flow humidified air cannula with inspired oxygen fraction (FiO2) 21% |
| PROCEDURE | Nasal air puffs | Nasal air puffs synchronized with the inspiratory time of the ventilator |
| PROCEDURE | propeller fan (FAN) | Stand-alone fan at the bedside directed toward the face of the patient |
Timeline
- Start date
- 2026-02-01
- Primary completion
- 2027-02-01
- Completion
- 2027-02-01
- First posted
- 2025-12-29
- Last updated
- 2026-01-29
Source: ClinicalTrials.gov record NCT07308171. Inclusion in this directory is not an endorsement.