NCT07306104

The Effect of Long-term Daily Stimulation of the Brain With Pulsed Electromagnetic Fields on Parkinsons Disease

The Effect of Long-term Treatment of Parkinson's Disease With T-PEMF

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: University of Southern Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn to what extent daily stimulation of the brain with transcranial pulsed electromagnetic fields (T-PEMF) works to treat persons with Parkinson's Disease. The main questions it aims to answer are: * How does 6 months of daily treatment (30 minutes/day) with T-PEMF affects neuro-mechanical and molecular biological factors compared with placebo treatment in persons with Parkinson's disease? * How does 12 months of daily treatment (30 minutes/day) with T-PEMF affects neuro-mechanical and molecular biological factors in persons with Parkinson's disease an does 12 months of T-PEMF alters the need for medication intake? The neuro-mechanical outcomes are compared with the "natural" progression of the disease as well as with a healthy reference group. Furthermore, it will be examined whether 12 months of T-PEMF treatment alters the need for medication intake. Participants in the intervention group will: * receive one 30 min treatment session daily for 12 months * receive either T-PEMF or sham treatment for the first 6 months * receive active T-PEMF treatment the last 6 months * visit for tests before treatment initiation, after 6 months of treatment and after 12 months of treatment.

Conditions

• PARKINSON DISEASE (Disorder)

Interventions

Type	Name	Description
DEVICE	Transcranial pulsed electromagnetic fields (T-PEMF)	30 min daily stimulation with transcranial pulsed electromagnetic fields (50 Hz)
DEVICE	Sham (No Treatment)	30 min daily the participants are using/wearing the T-PEMF device but no stimulation occurs

Timeline

• Start date: 2026-02-01
• Primary completion: 2028-01-01
• Completion: 2028-01-01
• First posted: 2025-12-29
• Last updated: 2025-12-29

Locations

2 sites across 1 country: Denmark