NCT07305142

Comparison of the Integrated Posterior-Anterior-Lateral Approach and the Posterior Approach in Robotic Radical Prostatectomy

A Prospective, Randomized Controlled Study Comparing the Integrated Posterior-Anterior-Lateral (PAL) Approach and the Posterior Approach in Robot-Assisted Radical Prostatectomy: Evaluation of Perioperative Outcomes, Postoperative Functional Recovery, and Oncologic Control

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: The First Affiliated Hospital of Zhengzhou University · Academic / Other
• Sex: Male
• Age: 40 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare perioperative, pathological, and early functional outcomes of PAL （Posterior, Anterior and Lateral）combined approach RARP and posterior approach (with Retzius space preserved) RARP in the treatment of prostate cancer.The main question it aims to answer was: What is the early therapeutic efficacy of robot-assisted laparoscopic radical prostatectomy using the combined posterior, anterior, and lateral (PAL) approach, and how does it compare with the traditional posterior approach? Participants were randomly assigned to undergo either robot-assisted laparoscopic radical prostatectomy using the PAL (posterior-anterior-lateral) approach or the classic posterior approach.

Conditions

• Urologic Cancer
• Prostate
• Robot Assisted Laparoscopic Radical Prostatectomy

Interventions

Type	Name	Description
PROCEDURE	PAL combined approach group	PAL combined approach was performed to resect the prostate
PROCEDURE	posterior approach group	Intraoperative resection of the prostate was performed by posterior approach

Timeline

• Start date: 2024-05-16
• Primary completion: 2025-12-01
• Completion: 2025-12-02
• First posted: 2025-12-26
• Last updated: 2025-12-26

Locations

1 site across 1 country: China