NCT07305129

PCV vs VCV in Low-Flow Anesthesia

Pressure-Controlled Versus Volume-Controlled Ventilation in Low-Flow Anesthesia: A Randomized Controlled Trial on Intraoperative Respiratory Mechanics and Postoperative Pulmonary Function

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: HULYA TOPCU, MD · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this observational study is to investigate the effects of ventilation modes on intraoperative and postoperative lung functions in patients under general anesthesia. This study aimed to compare the effects of low-flow anesthesia on intraoperative respiratory mechanics and early postoperative pulmonary function between PCV and VCV in ASA I-II adult patients.

Detailed description

Studies comparing the effects of pressure-controlled ventilation (PCV) and volume-controlled ventilation (VCV) on lung function under low-flow conditions are limited. In this study, the effects of PCV and VCV on intraoperative respiratory mechanics and early postoperative pulmonary function were investigated during low-flow anesthesia in ASA I-II adult patients undergoing routine anesthesia procedures.

Conditions

• ASA Class I/II Patients
• General Anesthetic
• Low Flow Anesthesia

Timeline

• Start date: 2023-07-01
• Primary completion: 2024-07-15
• Completion: 2025-08-01
• First posted: 2025-12-26
• Last updated: 2025-12-26

Locations

1 site across 1 country: Turkey (Türkiye)