NCT07304479

Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery

Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery on Airway Plateau Pressure: a Randomized, Prospective, Blinded Pilot Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: National and Kapodistrian University of Athens · Academic / Other
• Sex: All
• Age: 18 Years – 87 Years
• Healthy volunteers: Not accepted

Summary

Inhalational anesthetics, when used in abdominal surgery, offer advantages of lung protection and reduced alveolar inflammation. There is little literature, however, in the comparative use of sevoflurane versus desflurane anesthesia in patients undergoing abdominal robotic-assisted surgery and their effects on lung mechanics.

Conditions

• Respiratory Mechanics
• Intraoperative

Interventions

Type	Name	Description
DRUG	Sevoflurane (Volatile Anesthetic)	Sevoflurane for robotic assisted laparoscopic surgery
DRUG	Desflurane (volatile anesthetic)	Desflurane for robotic assisted laparoscopic surgery

Timeline

• Start date: 2025-05-01
• Primary completion: 2026-01-30
• Completion: 2026-02-28
• First posted: 2025-12-26
• Last updated: 2025-12-26

Locations

1 site across 1 country: Greece