Trials / Enrolling By Invitation
Enrolling By InvitationNCT07304193
Clinical and Genetic Aspects of Fetuses With Sex-chromosome Disorders
- Status
- Enrolling By Invitation
- Phase
- —
- Study type
- Observational
- Enrollment
- 120 (estimated)
- Sponsor
- University of Aarhus · Academic / Other
- Sex
- All
- Age
- 11 Weeks – 22 Weeks
- Healthy volunteers
- Not accepted
Summary
To conduct a comprehensive clinical investigation of electively aborted fetuses with sex chromosome disorders and their placentas, in parallel with analyses of epigenetic alterations and changes in gene expression in these fetuses and their placentas, with the aims to: 1. delineate how variations in sex chromosome number affect the epigenetic and genetic mechanisms regulating gene expression in the placenta and in multiple fetal tissues in fetuses with sex chromosome disorders; 2. identify the epigenetic and genetic mechanisms and placental and fetal alterations that underlie the phenotypic manifestations observed in fetuses with sex chromosome disorders.
Conditions
Timeline
- Start date
- 2024-01-01
- Primary completion
- 2029-12-31
- Completion
- 2029-12-31
- First posted
- 2025-12-26
- Last updated
- 2026-01-08
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT07304193. Inclusion in this directory is not an endorsement.