Trials / Completed
CompletedNCT07302945
A Single-volunteer Study of Immune Response Following OTS-412 Vaccinia Virus Systemic Injection(Self-experiment)
High-Resolution Immune Dynamics Following OTS-412 Oncolytic Vaccinia Virus Administration in a Healthy Volunteer(Self-experiment)
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 1 (actual)
- Sponsor
- Bionoxx Inc. · Industry
- Sex
- Male
- Age
- —
- Healthy volunteers
- Accepted
Summary
Following oncolytic virus (OV) administration, the host immune response is initiated immediately and evolves dynamically. However, in clinical OV therapy, it is virtually impossible to capture these immune events in real time. To address this gap, the principal investigator conducted a high-resolution immune monitoring study in a healthy volunteer.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | OTS-412 | After hospitalization, OTS-412 was infused for one hour. |
Timeline
- Start date
- 2022-01-04
- Primary completion
- 2022-01-14
- Completion
- 2022-05-02
- First posted
- 2025-12-24
- Last updated
- 2025-12-26
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT07302945. Inclusion in this directory is not an endorsement.