Trials / Completed
CompletedNCT07301840
Ultrasound-guided Erector Spinae Plane Block Versus Local Wound Infiltration in Breast Conservative Surgery
Ultrasound-guided Erector Spinae Plane Block Versus Local Wound Infiltration in Breast Conservative Surgery, Randomized Double Blinded Comparative Study
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 66 (actual)
- Sponsor
- Cairo University · Academic / Other
- Sex
- Female
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Abstract Background: Postoperative pain management is a crucial component of patient care following breast conservative surgery. This study compares the efficacy of ultrasound-guided Erector Spinae Plane Block (ESPB) and Local Wound Infiltration (LWI) in managing acute postoperative pain in these surgeries. Objectives: This randomized, double-blinded, controlled clinical trial aims to compare the analgesic efficacy and safety of ultrasound-guided ESPB and LWI in patients undergoing breast conservative surgery. Patients and methods: Adult female patients (aged 18-75, ASA II) scheduled for breast conservative surgery were randomly assigned to either the ESPB or LWI group. The primary outcome was total morphine consumption in the first 24 hours postoperatively. Secondary outcomes included; intraoperative fentanyl consumption, hemodynamic parameters (mean arterial blood pressure and heart rate), time of first rescue analgesia, postoperative pain scores, the incidence of postoperative nausea and vomiting (PONV) and patient satisfaction. Complications such as local anesthetic toxicity and respiratory depression were also assessed. Key Words: Erector Spinae Plane Block (ESPB), Local wound infiltration, Postoperative analgesia, Breast conservative surgery
Conditions
- Local Wound Infiltration
- Erector Spina Plan Block
- Nerve Block/Methods
- Post Operative Analgesia
- Pain Management
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Erector Spinae Plane Block | Typical ESPB |
| PROCEDURE | Local Wound Infiltration | Preemptive Local Wound Infiltration |
Timeline
- Start date
- 2024-08-21
- Primary completion
- 2024-12-23
- Completion
- 2024-12-23
- First posted
- 2025-12-24
- Last updated
- 2025-12-24
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT07301840. Inclusion in this directory is not an endorsement.