NCT07298746

Oct Angiography Changes After Local Anesthesia in Cataract Surgery

OCT Angiography Changes of Retinal Microvasculature After Local Anesthesia in Cases Undergoing Cataract Surgery

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Assessement of retinal microvasculature detected by OCT-angio after peribulbar \&retrobulbar anesthesia in cases undergoing cataract surgery .

Detailed description

prospective , interventional,comparative , clinical study utilizing a pre-post, within-subject design ,which will be conducted in the Department of Ophthalmology ,Sohag University Hospital ,Egypt. Optical coherence tomography angiography (OCTA) will be performed before and after the administration of retrobulbar and peribulbar local anesthesia in the same cohort of patients, in order to evaluate the immediate effects of the anesthetic intervention on retinal microvascular parameters.the study will be conducted on patients aged 40-80 years with elective cataract surgery requiring regional block.the study will be divided into two main groups : 1. Group with peribulbar anesthesia injection. 2. Group with retrobulbar anesthesia injection.

Conditions

• OCTA Changes With Local Anesthesia

Interventions

Type	Name	Description
DRUG	Local Anesthesia (peribular injection of both lidocaine 2 % and hyaluronidase 150IU\ML)	peribular injection of both lidocaine 2 % and hyaluronidase 150IU\\ML
DRUG	Local Anesthesia (peribulbar anesthesia injection of mepivacaine 2% and hyaluronidase 150IU\ML)	peribulbar anesthesia injection of mepivacaine 2% and hyaluronidase 150IU\\ML
DRUG	Local Anesthesia (retrobulbar anesthesia injection of lidocaine 2 % and hyaluronidase 150IU\ML)	retrobulbar anesthesia injection of lidocaine 2 % and hyaluronidase 150IU\\ML
DRUG	local Anesthesia (retrobulbar anesthesia injection of mepivacaine 2% and hyaluronidase 150IU\ML)	retrobulbar anesthesia injection of mepivacaine 2% and hyaluronidase 150IU\\ML

Timeline

• Start date: 2025-12-01
• Primary completion: 2026-12-01
• Completion: 2027-03-01
• First posted: 2025-12-23
• Last updated: 2025-12-23