NCT07298512

Clinico-radiological Correlation of MRI Findings in Patients With Temporomandibular Joint Disc Perforation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 282 (actual)
• Sponsor: Recep Tayyip Erdogan University Training and Research Hospital · Academic / Other
• Sex: All
• Age: 14 Years – 79 Years
• Healthy volunteers: Accepted

Summary

To evaluate the presence of TMJ disc perforation on MRI and investigate its associations with internal disc derangements, disc configuration, condylar bone marrow signal patterns, joint effusion, and demographic or clinical variables such as age, sex, dental status, and pain severity.

Detailed description

This study will prospectively evaluate temporomandibular joint (TMJ) disc perforation using magnetic resonance imaging (MRI) in a diverse adult population. The investigation will focus on identifying the prevalence of disc perforation and examining its relationship with key TMJ structural and functional parameters. Specifically, the study will assess internal disc derangements, variations in disc morphology, condylar bone marrow signal characteristics, and the presence of joint effusion. In addition, demographic and clinical factors-including age, sex, dental status, and pain severity-will be analyzed to determine their potential association with disc perforation. MRI-based assessments will be performed using standardized imaging protocols, and all findings will be systematically recorded and evaluated. By integrating radiologic and clinical data, the study aims to improve the understanding of factors contributing to TMJ disc perforation and to support future diagnostic and therapeutic strategies.

Conditions

• Temporomandibular Joint Disc Displacement
• Magnetic Resonance Imaging
• Bone Marrow

Timeline

• Start date: 2025-11-01
• Primary completion: 2025-12-03
• Completion: 2025-12-03
• First posted: 2025-12-23
• Last updated: 2025-12-23

Locations

1 site across 1 country: Turkey (Türkiye)