NCT07297615

3D Liver Volumetry

Accuracy of Individualized 3D Reconstruction in Predicting Liver Resection Volume: A Prospective Study

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Medical University of Graz · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study aims to improve preoperative evaluation of liver resection volume in patients undergoing major hepatectomies. Accurate prediction of the planned resection and the future liver remnant (FLR) is critical to minimize the risk of postoperative liver failure, which is associated with increased morbidity and mortality. Conventional imaging-based volumetry may have limited accuracy. This study investigates the use of individualized 3D liver models combined to enhance visualization and volumetric analysis of liver anatomy and resection boundaries. Patients are recruited in the liver outpatient clinic and, upon consent, preoperative 3D models are created using Medics 3D. During surgery, the planned resection is guided by the individualized 3D models. Postoperatively, the resected specimen undergoes CT-based volumetry to compare the predicted resection volume from the 3D model with the actual volume. Routine postoperative follow-up is conducted. The study aims to optimize surgical planning, enhance the accuracy of future liver remnant prediction.

Conditions

• Liver Surgery
• Liver Cancer
• Surgical Planning
• Liver
• Volumetric Analysis
• 3D-reconstruction

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	3d reconstruction	Preoperatively, every patient in this study will undergo an individualized 3D reconstruction of their liver to perform accurate volumetry.

Timeline

• Start date: 2026-04-01
• Primary completion: 2028-03-31
• Completion: 2028-09-30
• First posted: 2025-12-22
• Last updated: 2026-02-17

Locations

1 site across 1 country: Austria