NCT07296926

Distolingual Infiltration Verses Conventional Nerve Block in Mandibular Third Molar Extraction

Comparison of Efficacy of Distolingual Infiltration in Conjugation With Conventional Inferior Alveolar Nerve Block to Conventional Inferior Alveolar Nerve Block Alone for Extraction of Mandibular Third Molar

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Watim Medical & Dental College · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This randomized controlled trial will compare the effectiveness of adding distolingual infiltration to conventional inferior alveolar and buccal nerve blocks for mandibular third molar extraction. A total of 120 patients will be allocated into two groups. Pain during flap elevation and bone guttering will be assessed using the Visual Analogue Scale.

Detailed description

Mandibular third molar extraction is a common oral and maxillofacial surgery procedure that requires profound local anesthesia. Despite conventional inferior alveolar, lingual and buccal nerve blocks, the distolingual gingiva may remain non-anesthetized due to accessory innervation via the mylohyoid and other nerves. Distolingual infiltration may improve anesthesia in this area. This randomized controlled trial will enroll 120 patients requiring mandibular third molar extraction. Participants will be randomized into two groups: conventional inferior alveolar and buccal nerve block (Group A) and the same technique with additional distolingual infiltration (Group B). Pain during mucoperiosteal flap elevation and bone guttering will be recorded on a 0-10 Visual Analogue Scale. The primary objective is to determine whether distolingual infiltration improves pain control compared to the conventional technique.

Conditions

• Pain (Visceral, Somatic, or Neuropathic)

Interventions

Type	Name	Description
PROCEDURE	Conventional Inferior Alveolar and Buccal Nerve Block	Standard inferior alveolar and long buccal nerve block for mandibular third molar extraction.
PROCEDURE	Distolingual Infiltration plus Conventional Nerve Block	Distolingual infiltration (0.2 ml) administered in addition to conventional inferior alveolar during mandibular third molar extraction.

Timeline

• Start date: 2024-08-15
• Primary completion: 2026-02-15
• Completion: 2026-04-15
• First posted: 2025-12-22
• Last updated: 2026-01-06

Locations

1 site across 1 country: Pakistan