NCT07294989

The Effective Blood Concentration of Ciprofol

Median Effective Concentration of Ciprofol and Its Correlation With Bispectral Index: A Prospective Observational Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 101 (estimated)
• Sponsor: Peking University Shenzhen Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

1. Eligible patients were selected and enrolled in the study. 2. General anesthesia was induced using ciprofol in all participants, with standardized evaluation of consciousness levels during induction. 3. The patients' pain and cognition are followed up after surgery.

Conditions

• Thyroid Disease

Interventions

Type	Name	Description
DRUG	Ciprofol	Beginning with an initial target plasma concentration of ciprofol at 1.2 μg/mL. Assessments of the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale and Bispectral Index (BIS) values are performed every minute until the patient achieves a complete anesthetic state (defined as an MOAA/S score of 0).

Timeline

• Start date: 2025-07-01
• Primary completion: 2026-06-30
• Completion: 2026-06-30
• First posted: 2025-12-19
• Last updated: 2026-01-06

Locations

1 site across 1 country: China