NCT07294417

Bone Cement Augmented Transpedicular Screw Fixation Versus Cannulated Screws Fixation in Osteoporotic Spine

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Kafrelsheikh University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare the clinical and radiological outcomes of bone-cement-augmented transpedicular screw fixation versus cannulated pedicle screw fixation in patients with osteoporotic spines requiring posterior instrumentation, with respect to implant stability (loosening/pull-out), pain relief, functional recovery, and complication rates.

Detailed description

Osteoporosis of the spine presents a significant challenge in spine surgery, particularly when instrumentation is needed for stabilization. With declining bone mineral density, conventional pedicle screw purchase becomes unreliable, leading to increased rates of screw loosening, pull-out, and fixation failure. A relevant development in instrumentation has been the use of cannulated pedicle screws, sometimes in combination with cement-injectable systems, designed to allow cement to flow through the screw to reinforce fixation. Such systems have shown improved implant stability and lower failure rates in osteoporotic bone compared with solid screws.

Conditions

• Bone Cement Augmented Transpedicular Screw Fixation
• Cannulated Screws Fixation
• Osteoporotic Spine

Interventions

Type	Name	Description
PROCEDURE	Bone Cement Augmented Transpedicular Screw Fixation	Patients will be treated with bone cement augmented transpedicular screw fixation.
PROCEDURE	Cannulated Screws Fixation	Patients will be treated with cannulated pedicle screw fixation.

Timeline

• Start date: 2025-12-20
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2025-12-19
• Last updated: 2025-12-23

Locations

1 site across 1 country: Egypt