NCT07294404

Peripheral Relative Refractive Power of Orthokeratology Lenses

Effectiveness of Orthokeratology and Peripheral Retinal Refraction Changes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 53 (actual)
• Sponsor: Tianjin Eye Hospital · Academic / Other
• Sex: All
• Age: 8 Years – 15 Years
• Healthy volunteers: Accepted

Summary

Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia. The proposed mechanism of action is the induction of peripheral myopic defocus, which reduces relative peripheral hyperopia on the retina. This study aims to evaluate changes in relative peripheral retinal refraction before and after OK lens wear using wide-field multispectral retinal refractive topography. The study will also investigate the relationship between these retinal refractive changes and the effectiveness of OK in controlling axial elongation.

Conditions

• Myopia
• Myopia; Refractive Error

Interventions

Type	Name	Description
DEVICE	orthokeratology	All participants will be fitted with orthokeratology lenses of the same design. The primary objective is to assess changes in relative peripheral retinal refraction before and after lens wear.

Timeline

• Start date: 2020-01-10
• Primary completion: 2021-06-15
• Completion: 2021-10-19
• First posted: 2025-12-19
• Last updated: 2026-03-02

Locations

1 site across 1 country: China