NCT07292272

Halt Aging in Survivors of Blood Cancers: the HALTAging-1 Study

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 180 (estimated)
• Sponsor: University of Nebraska · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

Older survivors of blood cancer are at a high risk of accelerated biological aging, which increases their risk of developing multiple aging-related conditions. Whereas physical exercise can improve overall health, older cancer survivors do not meet the recommended physical activity, highlighting the need to develop behavioral interventions to increase adherence. Several other knowledge gaps exist to implement exercise interventions in older survivors of blood cancer; the dose and duration of exercise necessary to slow biological aging in older blood cancer survivors remain unknown. To bridge these gaps in knowledge, we have designed a Phase 2 randomized control trial to test the effects of behavioral and exercise interventions on various outcomes.

Conditions

• Hodgkin Lymphoma
• Leukemia
• Lymphoid Leukemia
• Multiple Myeloma
• Myeloid Leukemia
• Monocytic Leukemia
• Non-hodgkin Lymphoma
• Other Hematologic Condition

Interventions

Type	Name	Description
BEHAVIORAL	Supervised Exercise and Coaching	Intervention arm incorporating virtually supervised moderate-intensity aerobic exercise and behavioral intervention/coaching to improve adherence
BEHAVIORAL	Virtual Gym Membership	This arm will get access to a virtual gym membership only

Timeline

• Start date: 2026-03-01
• Primary completion: 2031-08-01
• Completion: 2032-03-01
• First posted: 2025-12-18
• Last updated: 2026-03-23

Locations

1 site across 1 country: United States