NCT07291765

Blood Flow Restriction Training in Acute Geriatric Rehabilitation: A Randomized Controlled Trial on Its Effects and Safety in Hospitalized Older Adults.

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University Hospital, Bonn · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

Background: Older adults have a reduced ability to build and maintain muscle mass due to age-related changes in the muscular system. The resulting sarcopenia can lead to a number of health problems and limitations, such as an increased risk of falling and reduced mobility, which can affect quality of life and increase the risk of disease. To increase muscle mass and strength, high-intensity resistance training with loads of 70 to 85% of the repetition maximum (1RM) is recommended. However, this type of training poses a major challenge in the rehabilitation sector, as there is also an increased risk of injury due to physical limitations in old age. According to current research, low-intensity occlusion training could therefore represent a safe and effective training alternative. The aim of this study is therefore to examine the feasibility and effects of blood flow restriction training (BFR) on general health in older adults in a rehabilitative setting.

Detailed description

The study is a randomized controlled trial with a pre-post design. The setting is the premises of St. Marien Hospital in Cologne. Participants will be recruited from the geriatric rehabilitation patient base. Patients will be randomized into 2 groups. The intervention group will be randomly assigned to receive BRF training on an exercise trainer five times a week over a period of two weeks, while the control group will receive sham-BFR training.

Conditions

• Sarcopenia in Elderly

Interventions

Type	Name	Description
DEVICE	Stationary Bike + Blood-Flow-Restriction	Cycling Intensity individualized + 60% LOP
DEVICE	Stationary Bike + Sham-Blood-Flow-Restriction	Cycling Intensity individualized + 20mmHg

Timeline

• Start date: 2026-01-01
• Primary completion: 2026-12-31
• Completion: 2027-03-31
• First posted: 2025-12-18
• Last updated: 2025-12-18

Locations

1 site across 1 country: Germany