NCT07291375

Role of Amlodipine in Reduction of CIN

The Effect of Low Dose Oral Amlodipine in Renal Protection From Contrast Induced Nephropathy in Diabetic Patients in Intensive Care Unit

• Status: Not Yet Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The aim is to assess the benefit of low dose oral amlodipine in renal protection from contrast induced nephropathy in diabetic patients in intensive care unit

Conditions

• Contrast-induced Nephropathy

Interventions

Type	Name	Description
DRUG	Calcium channel blocker	amlodipine group will receive low dose oral amlodipine ( 5 mg ) before iv contrast and every 12 hour for 48 hour
OTHER	Hydration	before the procedure patients will recieve iv bolus of 250 ml saline followed by continous infusion of 100 ml/h of normal saline

Timeline

• Start date: 2025-12-20
• Primary completion: 2026-06-01
• Completion: 2026-07-01
• First posted: 2025-12-18
• Last updated: 2025-12-18