NCT07291245

Kawasaki MATCH Trial

Kawasaki MATCH: A Clinical Decision Support Tool to Detect KD

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: University of California, San Diego · Academic / Other
• Sex: All
• Age: 30 Days – 17 Years
• Healthy volunteers: Not accepted

Summary

Evaluating the impact of a machine-learning clinical decision support tool on provider practice when evaluating febrile patients with Kawasaki Disease (KD) and non-KD illnesses.

Detailed description

Following laboratory evaluation, providers will be randomized to treat patients according to usual practice/standard of care vs. receiving clinical decision support from the Kawasaki MATCH tool - a previously validated machine-learning clinical decision support tool to identify Kawasaki Disease. The study aim is to evaluate the accuracy of Kawasaki MATCH prospectively when used at the point of care, as well as how this tool impacts clinical decisions including additional evaluation and hospital admission.

Conditions

• Kawasaki Disease

Interventions

Type	Name	Description
OTHER	Kawasaki MATCH	Providers access the Kawasaki MATCH decision support tool. Patient information is entered into the tool and a risk score is indicated to the provider. Kawasaki MATCH is a previously validated machine-learning decision support tool for the diagnosis of Kawasaki Disease. This tool utilizes patient age, 18 laboratory features, and 5 clinical features to formulate a risk score.

Timeline

• Start date: 2025-03-01
• Primary completion: 2026-10-31
• Completion: 2026-10-31
• First posted: 2025-12-18
• Last updated: 2025-12-18

Locations

1 site across 1 country: United States