NCT07290075

The Relationship Between Olfactory and Gustatory Senses, Hedonic Hunger, and Diet Quality After Bariatric Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 101 (actual)
• Sponsor: Hanife Köksal · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This cross-sectional observational study investigates the association between changes in olfactory and gustatory senses and hedonic hunger among individuals who have undergone bariatric surgery. The study also examines the effects of these sensory changes on diet quality and anthropometric measurements. Participants completed a structured questionnaire including sociodemographic and health information, dietary habits, a modified 33-item taste and smell assessment, the Power of Food Scale (PFS), the Mediterranean Diet Adherence Screener (MEDAS), the International Physical Activity Questionnaire (IPAQ), and anthropometric measurements.

Detailed description

Obesity is a chronic, multifactorial disease that negatively impacts health and quality of life. Bariatric surgery is an effective treatment option for severe obesity, leading to significant and sustained weight loss as well as improvement in obesity-related comorbidities. Postoperative changes in taste and smell perception are frequently reported by bariatric patients and may influence food preferences, hedonic hunger, and overall diet quality. These sensory alterations can result from anatomical and hormonal changes after surgery, including altered gut hormone secretion (e.g., PYY, GLP-1, ghrelin) and bile acid metabolism, which affect appetite regulation and reward pathways. This cross-sectional observational study evaluated adults aged 18-65 years who had undergone sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) at least three months prior to enrollment. Data collection included sociodemographic and health information, dietary habits, a modified 33-item taste and smell questionnaire, the Power of Food Scale (PFS) to assess hedonic hunger, the Mediterranean Diet Adherence Screener (MEDAS), the International Physical Activity Questionnaire (IPAQ), and anthropometric measurements. Nutrient intakes were analyzed according to the Türkiye Nutrition Guide (TÜBER-2022) reference values. The primary objective was to determine the relationship between postoperative taste/smell changes and hedonic hunger. Secondary objectives included assessing the association between sensory perception and Mediterranean diet adherence, anthropometric parameters, and nutrient adequacy by surgery type. Findings from this study may guide the development of personalized nutritional follow-up protocols to improve long-term outcomes in bariatric patients.

Conditions

• Obesity
• Taste Disorders
• Smell Disorder

Interventions

Type	Name	Description
OTHER	Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB)	Participants who have undergone sleeve gastrectomy ≥3 months prior to study enrollment; and Participants who have undergone Roux-en-Y gastric bypass ≥3 months prior to study enrollment.

Timeline

• Start date: 2024-01-01
• Primary completion: 2024-11-30
• Completion: 2025-01-31
• First posted: 2025-12-17
• Last updated: 2025-12-17

Locations

1 site across 1 country: Turkey (Türkiye)