NCT07289880

Efficacy of Diacylglycerol Oil on Metabolic Risk Factors in Prediabetes

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: The First Affiliated Hospital of Guangdong Pharmaceutical University · Academic / Other
• Sex: All
• Age: 40 Years – 75 Years
• Healthy volunteers: Accepted

Summary

This study will implement a four-week dietary intervention among middle-aged and older adults with pre-diabetes. Participants assigned to the intervention arm will replace their usual cooking oil with diacylglycerol (DAG) oil, while those in the control arm will consume colza oil. All other lifestyle behaviors will be maintained without modification. The trial will determine the impact of DAG oil consumption on glycemic regulation, lipid metabolism, and body composition in this high-risk population.

Conditions

• Prediabetes

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Diacylglycerol oil	This study will implement a four-week dietary intervention in which participants assigned to the intervention group will replace their habitual cooking oil with diacylglycerol (DAG) oil. All other lifestyle behaviors will be maintained without modification.
COMBINATION_PRODUCT	Colza Oil	Participants assigned to the control group will consume colza oil as their cooking oil throughout a four-week dietary intervention. No other lifestyle habits or dietary behaviors will be altered.

Timeline

• Start date: 2025-12-30
• Primary completion: 2026-12-01
• Completion: 2027-12-30
• First posted: 2025-12-17
• Last updated: 2025-12-24

Locations

1 site across 1 country: China