NCT07288762

Gonadal Function in Thalassemic Patient

Gonadal Function in Boys With Transfusion Depandant Beta Thalassemia

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: Male
• Age: 10 Years – 18 Years
• Healthy volunteers: Accepted

Summary

Patient with transfusion depandant beta thalassemia with accumulation of iron in their body affect pituitary gland and gonades lead to impaired their functions .

Detailed description

detection of any abnormalities in pituitary gland hormones ( FSH , LH , serum prolactin ) gonadal hormones ( serum testesterone , antimullerian hormone , INSL3 , inhibin B hormone )

Conditions

• Thalassemia Majors (Beta-Thalassemia Major)

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	serum inhibin B serum INSL3 serum AMH	transfusion depandant beta thalassemia with measure gonadal function serum INSL3 serum inhibin B serum AMH

Timeline

• Start date: 2025-12-07
• Primary completion: 2026-04-01
• Completion: 2026-08-01
• First posted: 2025-12-17
• Last updated: 2025-12-17