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Not Yet RecruitingNCT07288463

Hearing Loss and Genetic Risks for Alzheimer's Disease and Related Dementia

Hearing Loss and Genetic Risks for Dementia

Status
Not Yet Recruiting
Phase
N/A
Study type
Interventional
Enrollment
20 (estimated)
Sponsor
University of Southern California · Academic / Other
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

Hearing loss is a prevalent and modifiable risk factor for cognitive decline and dementia in older adults, yet access to hearing care remains limited. Over-the-counter (OTC) hearing aids represent a promising and scalable strategy to expand access, particularly for individuals at elevated risk for dementia who may benefit most from earlier intervention. This pilot study aims to evaluate the feasibility and acceptability of OTC hearing aid use among older adults at increased risk for dementia. Participants aged ≥50 years will undergo standardized hearing screening to identify bilateral, mild-to-moderate hearing loss. Eligible participants will be randomized to one of two sequences: (1) immediate intervention: 4-mo using OTC hearing aids or (2) waitlist control: 2-mo without devices followed by an additional 4-mo using OTC hearing aids. Feasibility outcomes include study enrollment and retention, protocol adherence, and average daily device use determined by data-logging. Acceptability outcomes will be assessed using the International Outcome Inventory for Hearing Aids (IOI-HA), device satisfaction ratings, and participant intention to continue hearing-aid use. Hearing outcomes include validated questionnaires on hearing and listenign efforts. Findings will inform the design of larger trials aimed at improving access to hearing care and promoting cognitive health in high-risk older adults.

Conditions

Interventions

TypeNameDescription
DEVICEOver-The-Counter (OTC) hearing aidOver-The-Counter (OTC) hearing aid

Timeline

Start date
2027-07-01
Primary completion
2030-06-30
Completion
2031-06-30
First posted
2025-12-17
Last updated
2025-12-17

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT07288463. Inclusion in this directory is not an endorsement.

Hearing Loss and Genetic Risks for Alzheimer's Disease and Related Dementia (NCT07288463) · Clinical Trials Directory