NCT07286851

Do Topical Antibiotics Improve Skin Graft Results?

Effects of Topical Neomycin on Skin Graft Outcomes in Rural Bangladesh: a Retrospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 142 (actual)
• Sponsor: LAMB Project · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this study is to see if putting antibiotic ointment on a skin graft when the surgery is being done helps prevent the skin graft from getting infected after the operation. The study is looking at all skin grafts done in a rural Bangladesh hospital. The main questions it aims to answer are: Does the antibiotic lower the number of infections that happen? Does the antibiotic make the overall outcome of the skin graft better? Do patients who get the antibiotic need fewer extra surgeries? Researchers will compare the outcomes from patients who had skin grafts before the hospital started applying antibiotic ointment to the outcomes of patients after the hospital began applying antibiotic ointment. Participants who have already had their skin graft treatment completed will have their medical records reviewed by researchers. The outcomes of their treatment will be written down.

Conditions

• Skin Transplantation
• Wounds and Injuries
• Antibiotic Prophylaxis Surgery

Interventions

Type	Name	Description
DRUG	Neomycin	Topical neomycin was applied at the time of split-thickness skin graft surgery.

Timeline

• Start date: 2024-12-01
• Primary completion: 2025-08-31
• Completion: 2025-08-31
• First posted: 2025-12-16
• Last updated: 2025-12-16

Locations

1 site across 1 country: Bangladesh