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Active Not RecruitingNCT07285265

Phase I Clinical Trial of Lyophilized Herpes Zoster mRNA Vaccine in Adults Aged 40 Years or Above

A Randomized, Blinded and Positive-Control Phase I Clinical Trial to Evaluate the Immunogenicity and Safety of Lyophilized Herpes Zoster mRNA Vaccine in Adults Aged 40 Years or Above

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
180 (actual)
Sponsor
Suzhou Abogen Biosciences Co., Ltd. · Industry
Sex
All
Age
40 Years
Healthy volunteers
Accepted

Summary

The primary objective of this study is to evaluate the tolerability, reactogenicity and safety of 2 injections (approximately 2 months apart) of three different dose levels of ABO1108 in adults aged 40 years or above.

Conditions

Interventions

TypeNameDescription
BIOLOGICALABO1108Formulation for injection
DRUGPlacebo0.9% sodium chloride (normal saline) injection
BIOLOGICALSHINGRIX• Formulation for injection

Timeline

Start date
2025-05-27
Primary completion
2025-11-06
Completion
2026-10-15
First posted
2025-12-16
Last updated
2025-12-16

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT07285265. Inclusion in this directory is not an endorsement.