Trials / Completed
CompletedNCT07284862
A Cross-sectional Study on the Association of Peptidoglycan Fragments Derived From Gut Microbiota With Alcohol Liver Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (actual)
- Sponsor
- Zhujiang Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Accepted
Summary
alcohol-associated liver disease (ALD) is a leading cause of cirrhosis, yet the role of gut microbiota-derived peptidoglycan (PG) metabolites in liver injury remains unclear. This study aimed to elucidate the role of microbial DL-endopeptidases, which generate NOD2 ligands, in modulating alcohol-induced liver injury.Participants will provide stool samples.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | An observational, non-interventional study design. | An observational, non-interventional study design. |
Timeline
- Start date
- 2025-07-01
- Primary completion
- 2025-11-01
- Completion
- 2025-11-01
- First posted
- 2025-12-16
- Last updated
- 2025-12-16
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT07284862. Inclusion in this directory is not an endorsement.