Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07284745

A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of KarXT + KarX-EC in Children and Adolescents (5 to 17 Years of Age) With Irritability Associated With Autism Spectrum Disorder

Status
Not Yet Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
176 (estimated)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
5 Years – 17 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess KarXT + KarX-EC for the treatment of irritability associated with autism in children and adolescents.

Conditions

Interventions

TypeNameDescription
DRUGKarXTSpecified dose on specified days
DRUGKarX-ECSpecified dose on specified days
DRUGKarXT + KarX-EC Matching PlaceboSpecified dose on specified days

Timeline

Start date
2026-09-11
Primary completion
2029-07-05
Completion
2029-07-05
First posted
2025-12-16
Last updated
2026-04-02

Locations

45 sites across 5 countries: United States, Argentina, Australia, Canada, India

Regulatory

Source: ClinicalTrials.gov record NCT07284745. Inclusion in this directory is not an endorsement.