NCT07284082

The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 90 (estimated)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Menopause is associated with the acceleration of many comorbidities, including cardiovascular disease. Whether HIV and menopause together increase cardiovascular disease risk is a key knowledge gap. The goal of this observational study is to address this knowledge gap by looking at the role of menopause on cardiovascular disease risk factors such as insulin resistance, hypertension, hyperlipidemia, and carotid atherosclerosis using previously collected data. The investigators will look at underlying causes for cardiovascular diseases worsening in menopausal women with HIV by looking at the role of increased inflammation in the body and whether this is altered by weight. The investigators achieve this by enrolling participants who are willing to undergo a whole body MRI.

Conditions

• HIV
• Menopause
• Cardiovascular (CV) Risk
• Carotid Arteriosclerosis
• Body Composition

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Whole body MRI	Whole body MRI will be performed as part of a study protocol

Timeline

• Start date: 2026-03-15
• Primary completion: 2030-03-01
• Completion: 2030-03-01
• First posted: 2025-12-16
• Last updated: 2026-04-08

Locations

1 site across 1 country: United States