Trials / Not Yet Recruiting
Not Yet RecruitingNCT07283068
IO Vancomycin Into the Medial Malleolus vs IV Administration in Revision TKA
Intraosseous (IO) Vancomycin Into the Medial Malleolus vs Intravenous (IV) Administration in Revision Total Knee Arthroplasty (TKA)
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- The Methodist Hospital Research Institute · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Purpose of this study is to compare the efficacy of intravenous and intraosseous antibiotic administration techniques during revision total knee arthroplasty
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Intraosseous Vancomycin | IO vancomycin is administered via an intraosseous cannulation device (Arrow EZ-IO; Teleflex, Morrisville, NC) in the OR after sterile prep of the leg and draping has occurred prior to skin incision (500mg in approximately 100mL NS). Injection will take place into the medial malleolus (within a pre-specified region) immediately prior to incision. |
Timeline
- Start date
- 2026-02-15
- Primary completion
- 2030-02-15
- Completion
- 2030-06-15
- First posted
- 2025-12-15
- Last updated
- 2025-12-23
Source: ClinicalTrials.gov record NCT07283068. Inclusion in this directory is not an endorsement.