NCT07280676

The Effect of Cosmetic Formulations on the Appearance of Grey Hair.

The Effect of Cosmetic Formulations on the Appearance of Gray Hair

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 380 (estimated)
• Sponsor: Unilever R&D · Industry
• Sex: All
• Age: 25 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study is a 6-month (180 days) single-center, double blind study designed to explore the effect of two cosmetic products on the appearance of gray hair.

Detailed description

This is a randomised, double blind, whole head study designed to evaluate the effect of two cosmetic leave on treatments on the appearance of gray hair. This study will accept up to 190 participants per cell (380 participants overall) who meet the inclusion/exclusion criteria to ensure that at least 150 participants per cell complete the study. Participants will be randomised to receive one of the two cosmetic hair products. The products will be applied to the whole scalp using a defined protocol. If accepted onto the study, participants will be provided with marketed shampoo and conditioner products for use throughout the study. Visual and instrumental assessments of hair color will be conducted throughout the duration of the study (6 months/180 days). Non-invasive skin surface samples will be collected at baseline, day 90 and day 180 for evaluation of target proteins and untargeted proteomic analysis of scalp and hair health.

Conditions

• Hair Graying

Interventions

Type	Name	Description
OTHER	U82	Cosmetic scalp leave on product
OTHER	Z63	Cosmetic scalp leave on product

Timeline

• Start date: 2025-12-15
• Primary completion: 2026-10-01
• Completion: 2026-10-01
• First posted: 2025-12-12
• Last updated: 2025-12-12

Locations

1 site across 1 country: United States