NCT07279285

Sweet-Tasting Solution Versus Placebo to Reduce Pain During Local Anesthetic Injection in Children

The Effect of a Sugar-free-flavored-sweet-tasting-solution on Pain Associated With Dental Injections in Pediatric Patients

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 54 (estimated)
• Sponsor: University of Jordan · Academic / Other
• Sex: All
• Age: 6 Years – 12 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn whether applying a sugar-free flavored sweet solution (SFSS) before local anesthesia helps reduce injection pain in children. The main question it aims to answer is: Does SFSS reduce pain during dental local anesthesia compared to a placebo (plain water)? Researchers will compare the use of SFSS and a placebo to see which results in lower pain scores. Participants will: Receive SFSS or placebo before local anesthesia during two dental visits Have their pain measured using self-reported and observational pain scales Have their heart rate monitored during the procedure

Conditions

• Injection Pain
• Local Anesthesia Infiltration
• Pain
• Injection Pain Prevention
• Pediatric Patients

Interventions

Type	Name	Description
OTHER	Sugar-free-flavored sweet tasting solution	A sugar-free-flavored sweet tasting solution that is anticipated to reduce the pain of local anaesthesia injections
OTHER	Placebo (sterile-water)	Placebo (sterile water)

Timeline

• Start date: 2026-01-01
• Primary completion: 2026-04-01
• Completion: 2026-04-01
• First posted: 2025-12-12
• Last updated: 2025-12-12