NCT07276009

Probiotics in Functional Dyspepsia

The Effect of Multi-strain Probiotic Formulation on Gastrointestinal Symptoms, Quality of Life and Mental Health in Patients With Functional Dyspepsia: a Randomized Dietary Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Nordic Biotic Sp. z o.o. · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn whether a multi-strain probiotic can reduce digestive symptoms and improve quality of life in adults with functional dyspepsia. The main questions it aims to answer are: * Does the probiotic reduce symptoms such as fullness after meals, bloating, stomach discomfort, and early satiation? * Does the probiotic improve emotional well-being, including stress, anxiety, and mood? Researchers will compare the probiotic to a placebo (a look-alike capsule with no active ingredients) to see if the probiotic truly helps adults with functional dyspepsia. Participants will: * Take one capsule of the probiotic or placebo once daily before meals for 60 days * Complete questionnaires about their digestive symptoms at the start, 1 month, and 2 months * Complete surveys on stress, anxiety, depression, and quality of life at the start and 2 months * Attend scheduled study visits for checkups and assessments

Conditions

• Functional Dyspepsia

Interventions

Type	Name	Description
OTHER	Lactobacillus	5 billion CFU of lactobacilus ans streptococci once daily for 60 days
OTHER	Maltodextrin (Placebo)	Placebo capsules will be given one a day for 60 days

Timeline

• Start date: 2026-01-05
• Primary completion: 2026-03-01
• Completion: 2026-05-01
• First posted: 2025-12-10
• Last updated: 2026-01-08