NCT07275593

Dexamethasone Versus Prednisolone in Acute Exacerbation of Childhood Asthma

Comparison of Outcome Between Dexamethasone Versus Prednisolone Administration in Acute Exacerbation of Childhood Asthma

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 224 (actual)
• Sponsor: Muhammad Aamir Latif · Academic / Other
• Sex: All
• Age: 2 Years – 12 Years
• Healthy volunteers: Not accepted

Summary

Because of insufficient local comparative data, this study was designed to determine the outcome of intravenous dexamethasone in contrast to oral prednisolone in acute exacerbation of asthmatic children.

Detailed description

The findings of this study would furnish the local data. The results would also provide recommendations to use more appropriate steroid options in the local settings, resulting in aid to improve the quality of life of asthmatic children and their quicker return to daily routine activities.

Conditions

• Acute Exacerbation of Asthma

Interventions

Type	Name	Description
DRUG	Dexamethasone	Patients received single IV dose of Dexamethasone at a dose of 0.6 mg/kg
DRUG	Prednisolone	Patients received oral prednisone at a dose of 2 mg/kg/day (max 60 mg) as a single dose for 3 days.

Timeline

• Start date: 2024-11-03
• Primary completion: 2025-04-03
• Completion: 2025-04-03
• First posted: 2025-12-10
• Last updated: 2025-12-10

Locations

1 site across 1 country: Pakistan