Trials / Not Yet Recruiting
Not Yet RecruitingNCT07275359
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations
- Status
- Not Yet Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 45 (estimated)
- Sponsor
- Duke University · Academic / Other
- Sex
- All
- Age
- 65 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to investigate the safety and tolerability of Metformin and how it changes blood markers associated with aging in persons who have chronic obstructive pulmonary disease (COPD) who do not have diabetes.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Metformin | All enrolled participants will receive open-label Metformin for a treatment period of 6 months. |
Timeline
- Start date
- 2026-09-01
- Primary completion
- 2027-03-31
- Completion
- 2027-09-30
- First posted
- 2025-12-10
- Last updated
- 2026-04-17
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT07275359. Inclusion in this directory is not an endorsement.