NCT07273799

Comparison of Outcomes Between Topical Minoxidil Versus Oral Minoxidil for the Treatment of Androgenetic Alopecia

• Status: Not Yet Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Sheikh Zayed Federal Postgraduate Medical Institute · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

To compare the outcome of topical minoxidil 5% spray versus oral minoxidil 2.5 mg tablet for the treatment of androgenetic alopecia in males and females. Outcomes include efficacy of the treatment, measured by reduction in hair shedding, improvement in hair density and new hair growth as assessed by physican and patient assessment as well as safety, defined as incidence and severity of adverse events over a treatment period of 6 months

Detailed description

This cohort, adaptive, randomized, double armed group, controlled, investigator-initiated interventional study is designed to demonstrate the superiority of a combination of Topical minoxidil vs oral minoxidil in patients suffering from androgenetic alopecia who consent to randomization following a new diagnosis in Pakistan. Conditions Androgenetic Alopecia Intervention/Treatment: Drug: Oral Minoxidil Drug: Topical Minoxidil

Conditions

• Androgenic Alopecia

Interventions

Type	Name	Description
DRUG	Minoxidil 5 % Topical Spray	Topical spray on hairs
DRUG	minoxidil	Oral minoxidil 2.5mg
DRUG	Placebo Spray	placebo spray
DRUG	Placebo Tablet or Capsule	Placebo tablet

Timeline

• Start date: 2025-12-20
• Primary completion: 2026-05-01
• Completion: 2026-06-01
• First posted: 2025-12-10
• Last updated: 2025-12-10