NCT07272408

Remote Ischemic Conditioning in Patients Undergoing Primary Percutaneous Coronary Intervention

Impact of Remote Ischemic Conditioning in Patients Undergoing Primary Percutaneous Coronary Intervention

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2 (actual)
• Sponsor: Helwan University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to detect the effects of remote ischemic conditioning on infarct size, global contractility, morbidity, mortality, and renal function in patients undergoing primary percutaneous coronary intervention.

Detailed description

Myocardial infarction (MI) generally refers to segmental (regional) myocardial necrosis, typically endocardial in location, secondary to occlusion of an epicardial artery. Primary percutaneous coronary intervention (PPCI) is a reperfusion therapy that is carried out in patients who usually have ST-segment elevation MI (STEMI) within a specific time window. During ischemia, metabolic acidosis occurs due to anaerobic metabolism, and ischemic injury ensues. After restoration of blood supply, reactive oxygen species (ROS) production and local inflammation increase secondary injury.

Conditions

• Remote
• Ischemic Conditioning
• Primary Percutaneous Coronary Intervention

Interventions

Type	Name	Description
PROCEDURE	Remote ischemic conditioning	Remote ischemic conditioning (RIC) was applied to those patients.
PROCEDURE	Normal primary percutaneous coronary intervention	Patients followed the standard primary percutaneous coronary intervention pathway.

Timeline

• Start date: 2022-09-01
• Primary completion: 2023-12-30
• Completion: 2023-12-30
• First posted: 2025-12-09
• Last updated: 2025-12-09

Locations

1 site across 1 country: Egypt