NCT07271199

Eyelash Effect Evaluation for Premium Rejuvenation Eyelash Serum

Evaluation of the Eyelash Care Effects of Premium Rejuvenation Eyelash Serum

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Hungkuang University · Academic / Other
• Sex: Female
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study aims to evaluate the efficacy of the Premium Rejuvenation Eyelash Serum on eyelashes and the surrounding periorbital skin. A total of 30 healthy female participants, aged 18 to 60, will be recruited and randomly assigned to two groups receiving different serum formulations. Participants will apply the product twice daily for 112 days (16 weeks), with eyelash and periorbital skin conditions assessed at multiple time points using non-invasive measurements. Key parameters include eyelash density, eyelash length, and overall periorbital skin condition. At the end of the study (Day 112), both participant self-assessments and evaluations by an eyelash specialist will be conducted to assess changes in eyelash and skin condition.

Detailed description

This prospective, randomized, double-blinded, placebo-controlled study aims to investigate the effects of Premium Rejuvenation Eyelash Serum on eyelashes and surrounding periorbital skin. A total of 30 healthy female adults aged 18 to 60 will be enrolled. Inclusion criteria require participants to be free from chronic diseases, major illnesses (including cancer, stroke-related disorders, paralysis, acute myocardial infarction, coronary artery bypass surgery, end-stage renal disease, or major organ/hematopoietic stem cell transplants), and allergic constitutions. Exclusion criteria include current use of medications or eyelash care products. Participants will be randomly assigned into two groups of 15 each: Group 1 uses placebo (Base formula without active ingredient); Group 2 uses the experimental formula with ginger (Zingiber officinale)-derived extracellular vesicle + turmeric (Curcuma longa)-derived extracellular vesicles + IGF-1 + FGF-7. . Baseline assessments will be conducted prior to product use. Follow-up assessments will occur at Days 28 (4 weeks), 56 (8 weeks), 84 (12 weeks), and 112 (16 weeks). Evaluations will include eyelash density, change in eyelash length, self-reported periorbital skin condition (e.g., swelling, irritation, pigmentation, redness, and allergic reactions), and a questionnaire. Eyelash parameters will be objectively measured using the Canfield Scientific VISIA® Skin Analysis System. At the conclusion of the study (Day 112), both participant self-assessments and evaluations by an eyelash specialist will be conducted to assess eyelash and surrounding skin condition.

Conditions

• Skin Condition
• Eyelash Growth
• Eyelashes
• Skin Health
• Hair Health

Interventions

Type	Name	Description
OTHER	Placebo control	Placebo Control (Base Formula without active ingredients). After thoroughly cleansing the face and removing contact lenses (if applicable), apply 1 mL of the serum evenly to the base of the eyelashes. Allow the serum to absorb for a few minutes. Repeat application twice daily, in the morning and evening.
OTHER	Experimental formula	Base formula with ginger (Zingiber officinale)-derived extracellular vesicle, turmeric (Curcuma longa)-derived extracellular vesicles, insulin growth factor-1 (IGF-1), and fibroblast growth factor-7 (FGF-7). After thoroughly cleansing the face and removing contact lenses (if applicable), apply 1 mL of the serum evenly to the base of the eyelashes. Allow the serum to absorb for a few minutes. Repeat this application twice daily, in the morning and evening.

Timeline

• Start date: 2025-11-01
• Primary completion: 2026-05-01
• Completion: 2026-05-01
• First posted: 2025-12-09
• Last updated: 2025-12-09

Locations

1 site across 1 country: Taiwan