NCT07269756

A Study to Evaluate the Drug Interactions of HRS-7535 With Acetaminophen, Digoxin, Rosuvastatin, and Omeprazole in Obese or Overweight Subjects

An Open, Fixed-sequence, Self-controlled Pharmacokinetic Study to Evaluate the Drug Interactions of HRS-7535 With Acetaminophen, Digoxin, Rosuvastatin, and Omeprazole in Obese or Overweight Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Shandong Suncadia Medicine Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study is an open-label, fixed-sequence, self-controlled Phase I clinical trial conducted among obese or overweight subjects, with a planned enrollment of 40 adult subjects.

Conditions

• Obesity
• Overweight

Interventions

Type	Name	Description
DRUG	HRS-7535 Tablets	HRS-7535 tablet.
DRUG	Paracetamol Tablets	Paracetamol tablet.
DRUG	Digoxin Tablets	Digoxin tablet.
DRUG	Rosuvastatin Calcium Tablets	Rosuvastatin Calcium tablet.
DRUG	Omeprazole Enteric-coated Capsules	Omeprazole Enteric-coated capsule.

Timeline

• Start date: 2025-12-08
• Primary completion: 2026-03-08
• Completion: 2026-03-08
• First posted: 2025-12-08
• Last updated: 2026-04-15

Locations

1 site across 1 country: China