NCT07268586

Intravenous Atropine in Reducing Reperfusion Arrhythmias, Conduction Abnormalities and Hypotension in Inferior ST-elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 158 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

People with acute inferior wall myocardial infarction will be given an intravenous drug called atropine that increases the heart rate to check if it prevents heart rhythm disturbances during performing coronary intervention

Conditions

• Myocardial Infarction

Interventions

Type	Name	Description
DRUG	Intravenous atropine immediately before wire crossing during primary percutaneous coronary intervention	Intravenous atropine 1 mg immediately before wire crossing during primary percutaneous coronary intervention
DRUG	Intravenous normal saline as placebo immediately before wire crossing during primary percutaneous coronary intervention	Intravenous normal saline as placebo immediately before wire crossing during primary percutaneous coronary intervention

Timeline

• Start date: 2025-08-01
• Primary completion: 2026-02-28
• Completion: 2026-02-28
• First posted: 2025-12-08
• Last updated: 2026-03-10

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study