NCT07267182

Gabapentin and Diclofenac Sodium Comparison for Post-Operative Pain Relief

Comparative Efficacy of Gabapentin and Diclofenac Sodium for Post-Operative Pain Relief in Patients Undergoing Major Abdominal Surgeries

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (actual)
• Sponsor: Muhammad Aamir Latif · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Little is known about comparative efficacy of gabapentin and diclofenac sodium in managing post-operative pain. Therefore, this study was planned to compare the efficacy of gabapentin, and diclofenac sodium for post-operative pain relief in patients undergoing major abdominal surgeries.

Detailed description

Non-steroidal anti-inflammatory drugs, opioid analgesics, and local and regional anesthesia have been used as preventive interventions, but their role in postoperative pain management remains inconclusive. Gabapentin is a relatively new drug for postoperative pain management whose side effects are well tolerated. If the findings of this study produce similar observations, it would add to the already scarce data and help patients undergoing major abdominal surgeries in the local settings in relieving postoperative pain effectively.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Gabapentin 600mg	Patients received a single oral dose of gabapentin 600 mg one hour before surgery.
DRUG	Diclofenac Sodium 100 MG	Patients were given a single oral dose of diclofenac sodium 100 mg one hour before surgery.

Timeline

• Start date: 2022-08-01
• Primary completion: 2023-02-28
• Completion: 2023-02-28
• First posted: 2025-12-05
• Last updated: 2025-12-05

Locations

1 site across 1 country: Pakistan