NCT07266051

Prospective Cohort Study of Neuromyelitis Optica Spectrum Disorders (NMOSD)

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 4,000 (estimated)
• Sponsor: Xiamen Hospital of Traditional Chinese Medicine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study aims to characterize sex hormone alterations and their potential clinical significance in NMOSD patients from Southern China through comprehensive hormonal profiling.

Detailed description

This study is a prospective cohort study, aiming to explore the characteristics of sex hormone levels in patients with neuromyelitis optica spectrum disorder (NMOSD). It plans to include 2,000 patients with NMOSD and 2,000 healthy controls, and conduct a 3-year follow-up. By regularly collecting data such as serum sex hormone levels, imaging, neurological function scales, and various biomarkers, the differences between the two groups will be compared and analyzed to reveal the role of sex hormones in NMOSD and their association with disease activity.

Conditions

• NMOSD

Interventions

Type	Name	Description
OTHER	Sex hormone assay	This study will explore and validate the characteristics of sex hormone levels in MNMOSD
OTHER	Sex hormone assay	This study will explore the comparison of sex hormone levels between a healthy control group and MNMOSD

Timeline

• Start date: 2025-12-01
• Primary completion: 2030-07-01
• Completion: 2030-12-01
• First posted: 2025-12-05
• Last updated: 2025-12-18

Locations

5 sites across 1 country: China