NCT07264751

The Effect of a Single Training Session on Changes in Inflammatory, Hormonal, and Metabolic Markers in Athletes.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 5 (actual)
• Sponsor: Poznan University of Physical Education · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Accepted

Summary

The study aims to assess the acute response of wrestlers to a single training session. Short-term changes in inflammatory, hormonal, and metabolic markers will be analyzed, which may reflect the development of fatigue and recovery processes following intense exercise. Participation in the study involves performing a standard training session and collecting blood samples at three time points to assess the physiological response. The results will provide a better understanding of the mechanisms of adaptation to exercise in strength and endurance athletes.

Detailed description

The study aims to assess how wrestlers' bodies respond to a single, intense training session. The study focuses on short-term changes in markers of inflammation, the hormonal system (stress hormones, catecholamines), and the metabolic system. This enables a deeper understanding of the physiological mechanisms underlying fatigue development and post-exercise recovery. Each participant will attend one standard training session, as outlined in the training plan. As part of the study, three venous blood samples will be collected: * Before training - at rest, to determine baseline values; * Immediately after training; * 24 hours after exercise - to evaluate recovery processes. Blood samples will be analyzed in the lab to determine: * inflammatory markers (hsCRP, IL-6, TNF-α), * muscle damage marker (CK), * stress hormones (adrenaline, noradrenaline, cortisol), * metabolic indicators (urea, creatinine, total protein, albumin, uric acid). The project does not require any additional supplementation, dietary changes, or modifications to the training plan. Participating in the study will provide insights into your individual body's response to intense exercise, including fatigue levels, inflammation, and hormonal balance. The results can help you better tailor your training load and improve your recovery. Participation in the study is completely voluntary. Participants may withdraw from participation at any time, without giving a reason, without any consequences. Withdrawal from the study will not affect their subsequent athletic training. All data obtained during the study will be treated confidentially and processed solely for scientific purposes. Results will be compiled in aggregate form, preventing the identification of individual participants. The study protocol was approved by the bioethics committee.

Conditions

• Training
• Inflammation Biomarkers
• Hormone
• Exercise Training

Interventions

Type	Name	Description
BEHAVIORAL	physical training	The intervention consists of a standardized, high-intensity wrestling training session designed to simulate typical strength-endurance exercise performed by elite wrestlers. The session includes sport-specific drills, resistance exercises, and aerobic conditioning components appropriate for this athletic discipline. All participants will perform the session under supervision to ensure safety and adherence to the planned intensity and duration.

Timeline

• Start date: 2014-02-01
• Primary completion: 2014-05-01
• Completion: 2014-06-01
• First posted: 2025-12-04
• Last updated: 2025-12-04

Locations

1 site across 1 country: Poland