NCT07262021

Visual Function of Enhanced Monofocal Intraocular Lenses

Comparison of Visual Function of Enhanced Monofocal Intraocular Lenses After Cataract Surgery

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Vienna Institute for Research in Ocular Surgery · Academic / Other
• Sex: All
• Age: 21 Years – 105 Years
• Healthy volunteers: Not accepted

Summary

Comparison of the visual function of two enhanced monofocal intraocular lenses after cataract surgery

Detailed description

Cataracts remain the leading cause of preventable blindness in many developing countries. Over the past decades, cataract surgery has undergone significant advancements. With the development of refined surgical techniques, such as smaller incisions, and the introduction of advanced intraocular lens (IOL) technologies, the procedure has transformed into a refractive approach for visual rehabilitation. The primary goal is to achieve a high level of spectacle independence for patient. Monofocal lenses are designed with a single fixed focal length and refractive power. While they provide excellent distance vision, patients still need glasses for intermediate and near vision. However, modern patients have increasingly high expectations, often seeking full independence from spectacles after cataract surgery. This growing demand has fueled ongoing research and innovation in the development of advanced IOLs. In contrast, enhanced monofocal IOLs offer optical properties that deliver good intermediate vision outcomes without the negative aspects of multifocal IOLs such as photic phenomena or loss in contrast vision. The aim of the study is therefore to compare two refractive enhanced monofocal IOLs in an intra-individual approach. 60 eyes of 30 patients will be included into this study. After randomization one eye is implanted with the Art 25 IOL, whereas the other eye gets the Eyhance IOL. Follow-up visits will be 1 week and 3 months after the surgery.

Conditions

• Cataract

Interventions

Type	Name	Description
DEVICE	enhanced monofocal IOL	Art 25 IOL, enhanced monofocal IOL
DEVICE	enhanced monofocal IOL	Eyhance IOL, enhanced monofocal IOL

Timeline

• Start date: 2025-12-01
• Primary completion: 2026-11-01
• Completion: 2027-11-01
• First posted: 2025-12-03
• Last updated: 2025-12-03

Locations

1 site across 1 country: Austria