NCT07261332

Early V/S Delayed Induction of Labour in Patients With Prelabour Rupture of Membranes

A Comparative Study on Early Versus Delayed Induction of Labour in Patients With Prelabour Rupture of Membranes at Term

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 88 (actual)
• Sponsor: Laiba Qamar · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

To compare the effects of early V/s delayed induction of labour and its outcomes in patients presenting with PROM without labour.

Detailed description

This is a comparative study where the patient who presented with PROM were assigned 2 groups of intervention . One had early induction of labour and other had induction of labour after 24 hours of observation. Both groups were compared for the average time of labour till delivery of the fetus and the frequency of spontaneous vaginal delivery was also calculated for each group.

Conditions

• Prelabor Rupture of Membranes
• Labor (Obstetrics)--Complications
• Induction of Labor

Interventions

Type	Name	Description
DRUG	0.5mg PGE2 gel	In this interventional group patients presenting with PROM will be immediately induced by 0.5mg PGE2 gel. If bishop score will not improve after 6 hours, then application of PGE2 gel will be repeated (maximum 2 doses)
DRUG	0.5mg PGE2 gel	The patients assigned with this intervention will be observed for 24 hours following which induction will be done using 0.5mg PGE2 gel in posterior fornix of vagina.

Timeline

• Start date: 2025-05-10
• Primary completion: 2025-10-10
• Completion: 2025-10-10
• First posted: 2025-12-03
• Last updated: 2025-12-03

Locations

1 site across 1 country: Pakistan