NCT07260968

Facilitating Lactation Through Optimized Workflows - Evaluating the Efficiency of Pumping Protocols and Cellular Mechanisms of Milk Production

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 225 (estimated)
• Sponsor: University of Rochester · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the effectiveness of two different breast pumping protocols in increasing milk production among lactating individuals diagnosed with primary low milk supply, and to investigate the associated molecular, hormonal, and inflammatory mechanisms driving milk output.

Conditions

• Low Milk Supply

Interventions

Type	Name	Description
OTHER	Pumping frequency intervention	In this randomized clinical trial, we will evaluate whether a lower frequency of pumping (3-4 times/day) or no additional pumping recommendations can lead to higher compliance, an increase in milk production, and a longer duration of breastfeeding.

Timeline

• Start date: 2026-04-01
• Primary completion: 2027-12-20
• Completion: 2028-09-30
• First posted: 2025-12-03
• Last updated: 2026-03-23

Locations

1 site across 1 country: United States