NCT07260097

Choroidal Venous Congestion Following Scleral Buckling - An Imaging Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Singapore National Eye Centre · Other Government
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

This study aims to understand how blood flow at the back of the eye changes over time after this surgery. By studying these changes, the investigators hope to gain insights that could help improve the understanding of other eye diseases, such as age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy(PCV). This research may contribute to better treatments and outcomes for future patients.

Detailed description

Scleral Buckling (SB) surgery emplaces a silicone band along the circumference of the eye to create an external support for retinal breaks, hence treating the retinal detachment. The investigators hypothesize that the presence of an external silicone band from the SB surgery would result in an increase in resistance across the choroidal venous outflow channels. This would in turn be manifested by quantitative and qualitative changes in choroidal vessel structure and architecture. These initial changes will eventually stabilise and revert to baseline after a period of long-term remodelling and adaptation. Through this imaging study, the investigators aim to opportunistically study and validate these progressive choroidal vasculature changes in the choroidal outflow circulation following scleral buckle (SB) surgery.

Conditions

• Pachychoroid Disease

Timeline

• Start date: 2025-07-17
• Primary completion: 2028-07-01
• Completion: 2028-07-01
• First posted: 2025-12-03
• Last updated: 2025-12-03

Locations

1 site across 1 country: Singapore